Weakness, coldness, insomnia… The body lacks it, and all kinds of problems come to your door!

The “first messenger” in our body is the human hormone. Human hormones are 100,000 to 100 million times smaller than the weight of a grain of salt, but they are very important. If there is a significant change or low in human hormones, it can cause serious health problems.

The changes in human hormones are completely different between men and women: women will have a significant decline in human hormones after the age of 49; while men have a gradual and slow downward trend. During this process, some people will be very sensitive and have difficulty coordinating their overall functions, leading to various organ dysfunctions.

 

There are four main symptoms of drastic changes in human hormones:

Symptoms of decreased physical fitness, prone to sweating and fatigue;

Symptoms of vasomotor, such as palpitation, fear of cold, fear of wind, etc.;

Mental and psychological symptoms, tantrums, memory loss, often insomnia;

Functional disorders, endocrine disorders, joint pain, etc.

 

If these symptoms occur, do not be too nervous or take it lightly, just make positive adjustments and treatments. People with mild discomfort can improve from three aspects.

1 Improve sleep

Adjust your drinking water. It is recommended that you do not drink or drink less water two hours before going to bed, and you can also exercise to consume physical energy.

For example, do a pendulum exercise, hold the back of the chair, touch one foot on the ground, and swing the other leg like a pendulum. Do 100 to 300 strokes on each side. Do not bend the knee joint. This movement can maintain the knee joint and exercise the thigh and pelvic floor muscles.

 

Another example is the levator ani exercise, which can improve pelvic floor muscle function, increase hormone secretion, and control urination by insisting on doing it for 10 minutes a day.

2 Control emotions

Don’t worry about too many things, try to pay more attention to your hobbies.

3 Adjust your diet

On the basis of a balanced diet, you can properly consume some meat, egg, milk, animal fat, milk and nuts to help regulate the level of hormones in the body.

If hormones in the body have seriously affected your life, you need to consult a professional physician for intervention and treatment, and the prognosis is usually good.

 

Today’s summary

The effect of human hormones on human health is produced unconsciously and is long-term. Therefore, we must pay more attention to the changes of various hormones in the body and make timely adjustments.

Pregnancy, heart disease must pay attention to!

Recently, the obstetrics department of Weifang people’s Hospital, together with cardiology department, cardiac surgery department, anesthesiology department and critical care department, has successfully rescued several pregnant women with late pregnancy and short-term postpartum heart failure. Most of them didn’t know they had heart disease before pregnancy, or they knew they had heart disease, but they felt young and asymptomatic, so they became pregnant blindly or continuously
Can pregnant woman have heart failure?
Whether primipara or multipara, should do a heart color Doppler ultrasound and ECG before pregnancy, to understand their heart function. Whether women of childbearing age can get pregnant and have children depends not only on their uterine and ovarian functions, but also on their cardiac functions.
The most common method to evaluate cardiac function is NYHA classification
I level, general physical activity is not limited, after exercise does not produce panic, shortness of breath and other discomfort.
Grade II, general physical activity was mildly restricted. After exercise, he felt flustered, shortness of breath, chest tightness and fatigue, and the symptoms disappeared after rest.
Grade III, severely restricted physical activity, slight activity, namely palpitation, shortness of breath, chest tightness, can be improved after rest; Or have had heart failure in the past, no matter how the heart function is now (unless the cause of heart failure has been removed by surgery), all belong to grade III.
Grade IV, can not carry out any physical activity, rest still have panic, shortness of breath and other discomfort.
If the heart function of women of childbearing age reaches grade III or even grade IV, it is better not to get pregnant before the heart function improves. Pregnant women during pregnancy, the body’s metabolic function is exuberant, the total amount of blood circulation increased by more than 30%. However, the enlargement of the uterus during pregnancy forces the diaphragm to rise, causing the heart to shift to the upper left, affecting the blood return, thus aggravating the burden on the heart. During labor, the uterus contracts, the parturient makes efforts, and the heart needs to run at full load. After the birth of the fetus, the abdominal pressure drops suddenly, and the placental blood circulation stops, which increases the amount of maternal cardiac blood, and the burden on the heart will suddenly increase. Therefore, pregnant women in late pregnancy and early postpartum are more prone to heart failure.
There are several cases of heart failure
All pregnant women with the following conditions are prone to heart failure, not suitable for pregnancy. If you are pregnant, it is recommended to consult a professional doctor in time
1. The heart disease is serious and the heart function is in grade III-IV;
2. Valvular heart disease with pulmonary hypertension or atrial fibrillation, infective endocarditis, or embolism after heart valve replacement;
3. Non cyanotic congenital heart disease (left to right shunt), atrioventricular septal defect and pulmonary hypertension;
4. Cyanosis (right to left shunt), tetralogy of Fallot, Eisenmenger syndrome;
5. No shunt type of moderate to severe pulmonary artery stenosis, aortic stenosis, Marfan syndrome and other high-risk heart disease.
How to reduce cardiovascular risk?
1. Keep a reasonable weight
Most pregnant women are overweight in late pregnancy, which undoubtedly brings many risks to heart burden and lower limb joints. Therefore, the weight should be controlled in a reasonable range before pregnancy, and the BMI value should be controlled in 24-26.
2. Stick to moderate exercise
Do not feel pregnant, we must lie still, recuperate. Moderate exercise can not only improve the cardiopulmonary function and cardiovascular adaptability of Baoma, but also reduce the risks of fetal production.
3. Abandon bad habits
Cigarettes contain many substances that harm blood vessels. In addition to affecting the health of pregnant women, it may even affect the fetus before birth because of second-hand smoke.
4. Reduce salt intake
Avoid pickled processed food, try not to eat preserved food such as instant noodles and canned food. In addition, it is best to reduce the intake of marinade, sauce, etc., and try to reduce the intake of salt.

Old asthmatic lungs become “silent lungs”

After more than 20 days of rescue, the man recovered and was discharged“ It’s yours. Don’t give up and let me get a new life On the morning of July 5, Mr. Chen, who was preparing to leave the hospital, recalled his racing with death for nearly a month, and his words were filled with gratitude.
Mr. Chen, 39, has been suffering from bronchial asthma since childhood. On the afternoon of June 11, when he attended the wedding banquet of his relatives, he suddenly developed asthma, and soon developed chest tightness and shortness of breath. His family quickly called 120 and sent him to the emergency department of the sixth Wuhan hospital (Affiliated Hospital of Jianghan University). At this time, Mr. Chen has fallen into a coma, blood oxygen saturation dropped to below 70%, blood pressure soared, heart rate is extremely fast. The consultation between respiratory and critical care doctors found that Mr. Chen’s lungs could not hear wheezing and breathing sounds at all. He was in the most serious state of “silent lung”, and his condition was very critical.
Mr. Chen’s mother told the doctor that his son had not visited the hospital for many years. Every time he got sick, he used the medicine he prescribed before. This attack was the most serious one. When the doctor was about to receive him to the respiratory and critical care unit, he opened his trachea and inserted a ventilator.
Li Fajiu, the director of the Department, said that 95% of asthma can be well controlled by doctors’ medication and patients’ self-monitoring. Unfortunately, in clinical practice, many patients with asthma only use drugs when they have attacks. Once their condition improves, they stop using drugs without authorization. This kind of intermittent use of drugs leads to the failure to maintain the proper concentration in the body, which greatly increases the risk of asthma recurrence.
“Irregular medication in remission period is an important cause of acute attack of asthma.” Li Fajiu reminds, symptom alleviates does not mean airway inflammation gets control. Asthma patients must comply with the doctor’s advice, even in remission should also regulate medication, and regularly review lung function. Don’t stop the drug by yourself, so as not to aggravate the disease and endanger life.

Eat right food can antiphlogistic!

Inflammation, anti inflammation, inflammation, anti inflammation… Although these words appear very frequently in our lives, do you really know what inflammation is?
Inflammation is a normal physiological reaction, when the tissue is stimulated by trauma, bleeding or pathogen infection, this reaction will be stimulated, the most typical performance is swelling, fever, pain. For example, when COVID-19 is infected with the lungs, the instinctive reaction of the cells is to eliminate the virus. But the lung cells themselves do not have the ability to destroy the virus. They need the help of the human immune system to kill the virus, and the immune cells gather in the lungs to form pneumonia.
Photo source: zhanku Hailuo
Inflammation can be divided into acute and chronic. The common acute inflammation includes gingival swelling and pain, tonsil inflammation, etc. Chronic inflammation is a widespread low-grade inflammation, which may last for weeks, months or years. It is often difficult to detect. It not only damages health, but also increases the risk of heart disease and cancer. Studies have shown that a reasonable diet can reduce the inflammatory reaction in the body, and some foods will aggravate the inflammation [1]. Next, let’s take a look at the “red and black list” of food related to inflammation.
Red List
Fruits and vegetables rich in antioxidants. In addition to vitamin C, fresh fruits and vegetables, especially dark fruits and vegetables (carrots, tomatoes, green leafy vegetables, etc.) also contain a lot of phytochemicals, such as polyphenols, lycopene, anthocyanins, carotene, etc. they have very strong anti-inflammatory and antioxidant effects, which help the human body produce natural killer cells and maintain the normal operation of the immune system. In addition, green leafy vegetables are also rich in magnesium, which can also hinder the development of chronic inflammation [1].
Fatty fish. The derivatives of omega-3 series fatty acids have the effects of lowering blood pressure, reducing inflammatory reaction and reducing blood coagulation, which are also beneficial for the prevention of cardiovascular disease [2]. Fatty marine fish are the main sources of omega-3 fatty acids, such as salmon, herring and mackerel. Studies have found that people who often eat salmon have relatively low levels of C-reactive protein (an indicator of inflammation).
Photo source: zhanku Hailuo
Spices. Star anise, fennel, pepper, ginger, cinnamon, in addition to giving food aroma, or anti-inflammatory master. For example, ginger contains gingerol, gingerol, gingerol and other active substances, which has antioxidant activity, can inhibit the production of inflammatory factors, and promote the synthesis of anti-inflammatory factors; Pepper contains piperine, eugenol, sesquiterpene and other active components, which have certain anti-inflammatory and antioxidant effects; Cinnamaldehyde and its derivatives in Cinnamomum cassia are anti-inflammatory components.
Green Tea. Green tea is rich in a variety of bioactive substances, such as tea polyphenols, theanine, theaflavins, caffeine, etc., which can inhibit the production of inflammatory mediators, control the development of inflammation, and have preventive and therapeutic effects on cardiovascular diseases [3].
Coarse grain. Brown rice, oats and other whole grains and red beans, mung beans and other miscellaneous beans have high dietary fiber content, rich in a variety of vitamins, magnesium and other minerals, and slow digestion speed, which can prevent blood sugar from rising suddenly and help control inflammation.
Blacklist
White staple food and sweet food. Hyperglycemia will increase the inflammatory response, so postprandial blood glucose should be controlled when there is inflammation. First, we should reduce the proportion of white rice and flour, eat less white steamed bread, white bread, white rice and noodles, and replace more than half of the staple food with coarse grain. Second, stay away from sugared foods such as candy, sweets, biscuits, cakes and sweet drinks, and eat less sugared foods such as sweet soup, porridge and fruit soup.
High fat food. Saturated fat can promote the occurrence and development of body inflammation, so when there is inflammation, you should eat less foods with high content of saturated fat, such as beef, pork, etc. You should also eat less fried food such as fried dough sticks and fried chicken. In addition, excessive omega-6 fatty acids (soybean oil, corn oil, sunflower seed oil and other edible oils) and trans fats (instant noodles, potato chips, chips and other processed foods) will also accelerate the development of inflammation. Therefore, it is necessary to control the intake of edible oil and eat less processed foods.
Processed meat. Processed meat products, such as sausages, hot dogs, ham and bacon, contain high content of saturated fat and certain pro-inflammatory components, which can aggravate inflammation. For the sake of health, this kind of food should be “occasionally eaten”, such as eating only two or three times a month, or enjoying it on weekends, holidays and festivals.

Three kinds of malignant tumors must not be treated with chemotherapy

With the continuous development of medical technology, there are more and more treatment methods for cancer. At present, the main treatment methods for cancer include surgery, chemotherapy, radiotherapy, targeted drug therapy, immunotherapy, interventional therapy and traditional Chinese medicine treatment.
Among them, many people have heard of chemotherapy, and many cancer patients think that all malignant tumors need chemotherapy. In fact, some cancers are not suitable for chemotherapy.
Not all malignant tumors are suitable for chemotherapy, especially the three
Chemotherapy refers to the use of chemical drugs to kill cancer cells, prevent the growth and proliferation of cancer cells, and promote the differentiation of cancer cells.
The purpose of chemotherapy is to eradicate cancer and make it no longer relapse; Reduce cancer cells or prevent cancer cells from continuing to grow and prevent cancer cells from spreading; To alleviate the symptoms of patients with disseminated cancer and improve the quality of life of patients.
Chemotherapy is a systemic treatment, which can play a role in the treatment of primary and metastatic lesions. It is a conventional treatment for a variety of malignant tumors.
However, the following conditions are not suitable for chemotherapy:
First, cancer that is not sensitive to chemotherapy
Although chemotherapy drugs can kill cancer cells, not all cancers are suitable for chemotherapy, such as pancreatic cancer, renal clear cell carcinoma, melanoma, cholangiocarcinoma and so on.
These cancers are very insensitive to chemotherapy and can not kill cancer cells at all, so chemotherapy is not recommended for this kind of malignant tumor.
Second, malignant tumors that have metastasized to the whole body
At this stage, chemotherapy is not only a waste of money, but also makes patients more painful, so chemotherapy is usually not recommended.
Third, malignant tumors in stage 1
At this time, the cancer cells did not have lymph node metastasis, which was found earlier. At this time, surgical resection was usually used, and chemotherapy was not needed.
In addition to the three types of cancer, chemotherapy is not recommended, there are also some cancer patients themselves are not suitable for chemotherapy.
These four kinds of people also do not recommend chemotherapy, often spend money to buy the guilty
The patient’s physical condition is too bad and the age is too old
Some cancer patients are suffering and consumed by cancer for a long time, resulting in poor nutritional status, often bony. In addition, if they are older, it is difficult to bear the side effects of chemotherapy, and the damage to the body is too great, so they are not suitable for chemotherapy.
Patients with chemotherapy intolerance
Such patients mainly include elderly patients and patients with serious side effects of chemotherapy. If such patients are forced to chemotherapy, it is easy to aggravate the development of the disease.
Patients with multiple chemotherapy without effect
After one or two courses of chemotherapy, it is necessary to check whether the focus has shrunk. If the condition has not been improved after many times of chemotherapy, it may be that the cancer cells have developed resistance to chemotherapy drugs, chemotherapy has been unable to control the development of the disease, and it is meaningless to continue chemotherapy, or even increase the suffering of patients.
For people who are not sensitive to chemotherapy drugs
Every patient’s constitution is different. Although chemotherapy drugs can kill cancer cells, they are not sensitive to every patient. Some patients are not sensitive to chemotherapy drugs, so chemotherapy has no effect, and such patients are not suitable for chemotherapy.
Diet is closely related to cancer. Three kinds of food can help prevent cancer
The relationship between diet and malignant tumor is very close. In order to prevent cancer, we should pay special attention to diet. Many people believe that some kind of food has anti-cancer effect, so they want to eat it every day.
In fact, no food has been found to have cancer fighting effect. However, food contains a lot of nutrients, which can resist oxidation, promote DNA repair, reduce the incidence of obesity, and reduce the risk of cancer.
The following three kinds of food have the auxiliary effect of preventing cancer:
Fresh fruits and vegetables
Vegetables and fruits contain little protein and fat, but they are rich in vitamin C, carotenoids, vitamin E, antioxidants, dietary fiber, flavonoids and other important phytochemicals.
Yang Binghui, chief physician of internal medicine of Zhongshan Hospital Affiliated to Fudan University and a famous health education expert in China, is also full of praise for the anti-cancer effect of vegetables and fruits. He believes that each person should eat 300 grams of vegetables every day, which can reduce the risk of gastric cancer by 50%.
Cabbage, asparagus, konjac, tomato, sweet potato, radish, carrot, kiwi and so on are all good food that can play an auxiliary role in anti-cancer.
Beans and bean products
Soy products such as soybean milk and tofu are rich in soy isoflavones. Regular intake of soy products can reduce the risk of colon cancer, breast cancer and cancer.
Beans and bean products are important sources of dietary fiber, high-quality protein and vitamins. They are rich in phytosterols and minerals, and do not contain cholesterol. If beans and cereals are eaten together, the utilization rate of protein can be increased through protein complementation.
Fungi
About 96% of fungi have auxiliary anti-cancer effect, such as Lentinus edodes, Auricularia auricula, mushrooms, Flammulina velutipes, etc. These foods are rich in polysaccharides, which can enhance human immunity and prevent lung cancer and gastric cancer.
At present, lentinan has been used as an anticancer drug in the treatment of cancer patients.
In addition, we should have a reasonable and balanced diet, pay attention to the combination of thick and thin food, have a complete range of food, eat less and eat more, have a sufficient quantity and a proper proportion, chew carefully and swallow slowly, do not overeat, and eat 70% or 80% full.
We should also appropriately eat more fish, poultry and eggs, reduce the intake of red meat, eat less fried food, do not eat moldy food.

What method does cure cancer pain have? Is taking painkiller addictive?

According to the latest data of the World Health Organization, 4.57 million new cancer cases will occur in China in 2020, accounting for nearly 1 / 4 of the world. Cancer patients, especially advanced patients, will suffer from more than 10 symptoms and syndromes, among which cancer pain is one of the most common symptoms.
According to statistics, the incidence of pain in newly diagnosed cancer patients is about 25%, while that in advanced cancer patients can reach 60-80%, of which 1 / 3 is severe pain. Cancer pain devastates the body and mind of patients and seriously affects their quality of life. Not only the patients themselves, but also their families were affected by the pain. Therefore, cancer pain management is actually saving the whole family.
At present, what is the new progress of cancer pain treatment? What are the common mistakes? Listen to the cancer pain management experts.
What does No.1 cancer pain have?
According to Dr. uzondu Osuagwu, an expert in cancer pain management at MD Anderson Cancer Center, cancer patients are usually afflicted by three types of pain:
1. Cancer related pain;
2. Cancer treatment-related pain (caused by surgery, radiotherapy, drug treatment, etc.);
3. Non cancer related pain (pain caused by other complications, social and psychological factors, such as low back pain, may occur before or after cancer diagnosis).
What’s the new progress in the treatment of No.2 cancer pain?
At present, there are several common methods to treat cancer pain
1. Drugs;
2. Intervention therapy, such as surgery or other therapies;
3. Alternative therapies, such as acupuncture, massage, physical therapy, etc. Professional cancer pain management team will treat the patients as a whole, not just for the symptoms themselves. Therefore, these methods (Integrated Traditional Chinese and Western Medicine) are usually used in pain management.
At present, in the field of cancer pain treatment, the most remarkable progress is spinal implant drug delivery. It allows us to achieve the goal of treatment at a lower dosage, which in turn reduces the incidence of side effects.
Another development is neural regulation technology, including spinal cord electrical stimulation or peripheral nerve block. We do this by using temporary devices or permanent implants. Both use electrodes to regulate the signals sent to the brain, so as to achieve analgesic effect.
Neural regulation technology is still a rapidly developing field. But we have seen that temporary devices can be removed only 30-60 days after implantation, and some patients will feel significant pain relief at this time. Some patients feel very good and report such a significant change after the trial (the test phase before the actual implantation of the device), and they can even do something that they have not been able to do for many years.
What are the common mistakes in the treatment of No.3 cancer pain?
Cancer pain to bear first?
“Forbearance” is praised by traditional Chinese culture. Many patients ask doctors to prescribe painkillers when the pain is unbearable. For cancer pain, you can’t bear it. Because cancer pain itself is a disease, poor pain management not only seriously affects the physical and mental health and quality of life of patients, but also has a serious impact on treatment.
The most ideal living condition of cancer patients should be painless life.
Are you afraid that painkillers are addictive?
About 75-90% of patients with advanced cancer need opioids for pain relief, but many patients will worry about drug addiction. In fact, oral opioid controlled-release and sustained-release formulations are not easy to addict.
Many patients can not bear the pain, they asked the doctor to give an injection of dolantin to relieve pain. In fact, who does not recommend the use of dolantin for the treatment of cancer pain, because it not only has poor effect and short action time, but also has neurotoxicity after long-term use. In addition, some common painkillers (such as non steroidal anti-inflammatory drugs) are not absolutely safe, and there is a “ceiling effect”.
Some patients only take painkillers when they are in pain, or stop taking them without permission. In fact, cancer pain is also a chronic disease. Taking medicine on time can maintain the stability of drug concentration and effectively control pain. Nonstandard drug use or discontinuation without authorization will cause a series of adverse reactions and affect the therapeutic effect.
Therefore, cancer patients should not make their own decisions. They should follow the “ladder principle” and follow the doctor’s advice to take appropriate analgesic drugs. If you feel that the pain management is good, you can adjust the medication under the guidance of the doctor.
Can’t painkillers be taken with other drugs?
Painkillers and other drugs can be taken together, but do not take all kinds of drugs together, so as to avoid mutual reaction between different drugs, or even toxicity. It is better to take each drug at a short interval.
Finally, I hope that cancer patients on the road to cancer, as far as possible less pain, more dignity.

Eating once is equal to drinking 1 barrel of oil. A 31 year old woman has osteoporosis because she likes to eat one kind of food

As an important pillar of our body, bone plays a key role in our health, but few people care for it. Especially now some young people do not pay attention to diet, usually eat and drink, do not like exercise, stay up late for a long time, resulting in more and more fragile bones. Once the occurrence of back pain, only to realize the importance of bone maintenance. However, it is difficult to recover to the previous level if there is a problem. Not only 31 year old Xiao Chen was diagnosed with severe osteoporosis some time ago.
Xiao Chen, 31, came from the countryside. When he was a child, his family conditions were not very good. In order to let his two younger brothers go to school, he dropped out of school at the age of 16 and went out to work in the city to earn money. Sometimes, he has to work several jobs a day, and Xiao Chen is frugal at ordinary times. He eats two meals a day in order to save money. Moreover, they often eat pickled vegetables with steamed bread and cakes. Occasionally, they want to change their taste. They also cook and package instant noodles to save money and pay their brothers’ tuition fees.
But just at the end of last month, when Xiao Chen was serving food to the guests, there was water on the ground. She accidentally slipped on the ground, sweating with pain, and could not stand up. Next to the shop assistant to see, quickly hit 120, she was sent to the hospital. I didn’t expect that this fall broke Xiao Chen’s bone. The doctor checked Xiao Chen’s bone density and found out osteoporosis.
Eating once is equal to drinking 1 barrel of oil. A 31 year old woman has osteoporosis because she likes to eat one kind of food
Through the communication between the doctor and Xiao Chen, we learned that the root cause of osteoporosis in Xiao Chen is malnutrition. He usually eats too simple meals and often eats pickles. Then during the process of making pickles, a lot of salt is put in. The sodium ion in the salt enters the body and needs to be excreted through the kidney, In the process of excreting sodium ions, the kidney will also excrete calcium ions from the kidney. If you eat too much salt, you will lose more calcium. In addition, Xiao Chen’s diet structure is relatively simple, so the body’s calcium is not much. Over time, osteoporosis is induced.
In addition to pickles, these two kinds of food should also be eaten less
1、 Food containing phosphorus
Many people like to eat lean meat, animal viscera and so on. These kinds of food contain too much phosphorus. We need to maintain a certain proportion of calcium and phosphorus in our body to help the transformation and utilization of calcium. If we eat too much food with high phosphorus content, it will reduce the transformation and utilization rate of calcium, imbalance the proportion of body concept, and affect the absorption of calcium.
2、 High sugar food
Like biscuits, cakes and other sweets, many people like to eat, but this kind of food in the production process will add a lot of sugar, although it can provide the energy our body needs, but too much sugar into the body, in the metabolic process will generate acid, the body in order to maintain acid-base balance, will release calcium from the bone, resulting in the loss of calcium.
Three things should be insisted on to maintain bones
(1) Reasonable diet
In the diet, according to their own situation, increase the intake of calcium rich foods, such as milk, shrimp, soybeans, etc. in addition, try to stay away from tobacco and alcohol, drink less strong tea, coffee and carbonated drinks.
(2) Keep moving
Exercise can not only enhance our immunity, but also promote the absorption of calcium in the body, enhance the strength of muscles and bones, and reduce the loss of calcium. In addition, some flexibility exercises can also reduce the risk of falling.
(3) Nutrition supplement
Once osteoporosis is found out, simple calcium supplement is not enough. It is necessary to eat some nutrients to maintain bones. Eating natriuretic peptide often helps to enhance the hardness of bones and promote the formation of bone matrix. At the same time, it also helps to transform the free calcium in the body into calcium which is easy to be used by the bone, so as to improve the bone density and make the bone more tough.

Natural insulin found

From kitchen 40 years, only food and love can live up to! We are looking forward to making friends with you who like delicious food. You are welcome to “pay attention” to me! The chef will cook with you.
01
Cool in summer
Into the hot summer, the temperature soared, people’s appetite seems to be scared by the hot weather, see what also feel greasy, no appetite. If you go into the kitchen to cook in such a hot summer day, you will feel like being washed and sweating after a while. Therefore, that kind of light and delicious, simple and easy to operate Qingkou dishes, has become the most popular “fragrant cake”. If it has the function of clearing away heat, clearing heart and calming the mind, it would be better, just like a trace of coolness in summer. Today, I recommend a kind of food that is especially suitable for summer to my friends, and this kind of food has more important benefits for human body. Natural “insulin” was found, summer to eat cool, 3 minutes out of the pot on the table was robbed.
02
Natural insulin
This kind of food is the most homely bitter gourd, also known as balsam pear. Just listen to the name, you feel much cooler this summer. Because the surface of balsam pear is pitted, like the back of “toad”, it is also called “toad”. Although balsam pear is leprous, its benefits and effects on human body are not leprous at all. Momordica charantia contains a kind of natural “insulin-like” substance, which has a good effect on reducing the sugar content in blood vessels. It is worthy of the name of “natural insulin”. Balsam pear is cool in nature and bitter in taste. It can be used in summer to clear away heat, calm the mind, clear the eyes and moisten the skin. Today, let’s use balsam pear to make a light, simple and delicious stir fried balsam pear. It is also a very easy dish, especially suitable for novices in the kitchen.
03
Stir fried balsam pear
Ingredient: 2 balsam pear
Ingredients: 30g water hair fungus, 10g green onion
Seasoning: 30g vegetable oil, 5 TSP water, 2G salt, 2G sugar, 2G monosodium glutamate or chicken powder (optional), 5 TSP Lake powder
04
Production process
1. Put seven or eight dried Auricularia into a bowl, pour in plenty of warm water and soak for several hours until full and moist. Remove the hard roots of Auricularia auricula, tear them into small leaves, and wash them twice again. Cut 10 grams of scallion, do not use ginger, garlic.
2. Two medium-sized balsam pear, clean, cut from the middle, remove pulp. If you are afraid of bitterness, remove the flesh thoroughly, and the bitterness will be reduced a lot. Then cut the single bitter gourd into 2 pieces, and wipe the oblique knife into oblique pieces. In this way, the fried bitter gourd is particularly crisp.
3. Pot into 30 grams of vegetable oil, oil temperature reached 56% heat, into the onion pan out of the incense. Immediately put in the bitter gourd block, water hair fungus small flower, pour in 5 teaspoons of water, open the fire, quickly stir fry until the bitter gourd is broken. Add 2G salt, 2G sugar, 2G monosodium glutamate or chicken powder (optional), seasoning and stir fry again.
4. Pour in 5 small spoonfuls of starch, see starch slightly gelatinized, stir fry evenly immediately. Cease fire, Pan Sheng pan, less than 3 minutes, this fried bitter gourd on the completion. Natural “insulin” has been found. In summer, you need to eat cool food to get rid of the heat. You need to eat bitter gourd every three minutes.
05
Cooking tips
1. If you can’t get used to the bitter taste of balsam pear, don’t worry. Share a little trick with friends: most of the bitter taste of balsam pear comes from the inner pulp of balsam pear. If you clean up the pulp of balsam pear, the bitter taste will be reduced a lot, and it won’t be so bitter to eat.
2. Spread a little knowledge of cooking, thicken: This is the most commonly used cooking technique in Chinese cuisine. By mixing an appropriate amount of water and starch, and through the “gelatinization” of starch, a uniform layer of thicken is formed, tightly wrapping the ingredients. It’s a very practical way to taste delicious.

AstraZeneca covid vaccine is associated with a slightly increased risk of hemorrhagic disease

The new crown is in the global pandemic, and vaccines are expected to restart the world. However, reports of thrombocytopenia and adverse events related to the Oxford AstraZeneca new crown vaccine, cdadox1, have led to restrictions on their use in some countries, while reducing the enthusiasm of some public vaccinations to some extent.
At 23:00 p.m. on June 9, Beijing time, a study by the British team was published online by the international top academic journal Nature Medicine entitled “first dose cadadox1 and bnt162b2 covid-19 vaccines and thrombocytopenic, thromboembolis and hmorrhagic events in Scotland”. The study conducted a national survey of more than 2.5 million Scottish adults who had received the first dose of Oxford AstraZeneca new crown vaccine, chudox1 or Pfizer biontech new crown vaccine bnt162b2. The survey showed that oxfordiicon vaccine was associated with a slight increase in the risk of an autoimmune haemorrhagic disease, i.e. Immunet thrombocytopenic purpura (ITP). The study also found that there may be evidence that Oxfam AstraZeneca vaccine is associated with increased risk of other bleeding and vascular problems.
The UK team stressed that public health authorities should inform their jurisdictions of these relatively small risk increases associated with the chdox1“ If the new crown vaccine is adequately supplied, it may be necessary to provide the public with alternative vaccines. ”
Nature medicine also published with the journal opinion articles written by Douglas B. cines, et al. Of the University of Pennsylvania. Cines et al. Stressed that it is important not only to consider the strengths and limitations of the study itself in interpreting the findings of this newly published study, “but also to consider a broader clinical background and the balance between the risks and benefits of vaccination.”
1.13 cases were given the first dose of every 100000 cases
The three vaccines currently used in the UK are Oxford AstraZeneca new crown vaccine, cdadox1, Pfizer biotech new crown vaccine bnt162b2 and Moderna company mrna-1273, which have been shown to reduce covid-19 infection. Given that the first mrna-1273 was only conducted in Scotland on April 7, 2021, the study focused on chdox1 and bnt162b2.
Previous clinical trials have shown that the two vaccines against COVID-19, ChAdOx1 and BNT162b2, are generally well tolerated, but a few serious side effects are reported. After 22million first and 6.8 million second injections, the British drug and health care products Administration (MHRA) received 209 cases of thrombocytopenic purpura and thromboembolism (haemorrhagic and thromboembolism, respectively).
The European drug administration also listed thrombocytopenia with thrombocytopenia as a rare side effect of the AstraZeneca vaccine in April, but still found that the benefits of vaccination were greater than the risk, and EU Member States decided whether to continue using it.
To investigate the possibility of a new crown vaccine and the progression of blood diseases, Aziz Sheikh and colleagues from the University of Edinburgh, UK, investigated vaccine related bleeding and vascular events in Scotland (57 per cent of adults over 18) who received the first new crown vaccine (most commonly, chdox1 or bnt162b2) between december2020 and April 2021.
The team found that in the survey population, the cdadox1 vaccine was associated with a slight increase in ITP risk for up to 27 days after injection, which led to mild cyanosis and excessive bleeding in some patients, and chronic disease in some patients. It is estimated that 1.13 of every 100000 first dose injections occur.
The analysis also showed that the risk of other arterial thrombosis and bleeding events increased slightly within 27 days of the treatment with chdox1. But there is no sufficient evidence that chadox1 is associated with a cerebral venous sinus thrombosis, a rare disease that forms thrombosis in the brain.
At the same time, the team did not find evidence that bnt162b2 vaccine was associated with the increased risk of these adverse events.
The research team points out in the paper that several limitations of the study should be paid attention to. Since few people were vaccinated with two doses at the time of analysis, no separate investigation was conducted on this subgroup (second dose), and further analysis of the second dose would be carried out at the appropriate time.
In addition, the study had fewer young vaccinations (< 40 years old), especially the cdadox1 vaccine, because the vaccination program has so far given priority to older and potentially basic disease groups. They noted that further research needs to be included in younger populations and to assess responses to a second dose of vaccine.
Limitations also include the need to assume that clinicians have conducted appropriate investigations of thrombocytopenia before recording ITP diagnosis.
The team concluded that in patients vaccinated with bnt162b2, they did not find an increase in the overall risk of any adverse events. The first dose of chdox1 was associated with a slight increase in ITP risk, suggesting an increased risk of arterial thromboembolism and bleeding events.
Given the slight increase in these risks in chdox1, the study believes that it may be necessary to provide the public with alternative vaccines if the new crown vaccine is adequately supplied.
The “balance between risk and benefit” team also stressed that the benefits of chadox1 are very clear and should be understood in this context. The novel coronavirus pneumonia risk is far less than that of the new crown pneumonia, especially for the elderly and other vulnerable groups.
The team said it is important to note that these small risks are important but rare, and are comparable to those of other vaccines, including hepatitis B, cysticercosis, mumps, rubella and influenza.
Cines and others wrote in the opinion article that the world has brought the fastest and the most extensive vaccination program in human history to control COVID-19’s efforts. Despite its many advantages, it has potential side effects, including autoimmune responses.
Cines et al. Stressed that it is important not only to consider the strengths and limitations of the study itself when interpreting the findings of the latest study published in nature medicine, “but also to consider a broader clinical background and the balance between the risks and benefits of vaccination.”
This article holds that, in general, the view that vaccination may induce immune thrombocytopenic purpura is not new and there is no precedent in the history of vaccine. For example, thrombocytopenia is common in children vaccinated against measles. The risk of ITP is generally mild and will subside in a few weeks or months. It is estimated that one case is found in every 40000 doses of measles mumps rubella vaccine, which is only slightly higher than that after natural infection.
Cines et al. Believes that the attribution of a rare adverse event to the vaccine will aggravate the phenomenon of “vaccine hesitation” and have an important impact on public health“ Overall, the author concludes that there is no clear evidence that ITP is associated with the first dose of bnt162b2 vaccine, and that the chadox1 vaccine may increase the risk of ITP. ”
They believe that the incidence rate, severity, duration and responsiveness of ITP after vaccination are not yet fully defined and need further analysis. Nevertheless, the risk of vaccine induced ITP seems to be far lower than many of the risks associated with covid-19. ”
Cines et al. Noted that some major international efforts are still ongoing to continue to assess and improve vaccine safety.

A variety of inexpensive steroids can improve survival in patients with severe COVID-19

A meta-study published on September 3 in JAMA confirms that multiple types of steroids can improve survival in patients with severe COVID-19, making inexpensive drugs a standard of care.

The meta-study, led by the World Health Organization, found that among severely ill patients who needed extra oxygen, the steroid group reduced the risk of death by about a third in the first month, compared with those treated with placebo or conventional care.

Dr Martin Landray, of the University of Oxford, who led one of the studies, said: “This result opens up more options for treating COVID-19. The more choices you have in terms of usability, the better.”

Dr Anthony Gordon, of Imperial College London, called the results a huge step forward, but added: “While these results are impressive, they do not cure disease.”

In June, a large study led by the University of Oxford found that a steroid called dexamethasone reduced death rates by 35 percent among hospitalized COVID-19 patients who needed a ventilator, and by 20 percent in patients who only needed additional oxygen. It does not help in milder patients and may even be harmful when used at that stage of the disease.

The results immediately changed the approach to treatment.

The new study analyzed six earlier discontinued studies, as well as the Oxford study.

There were 222 deaths among 678 patients who took steroids and 425 among 1,025 patients who took placebo or conventional treatment.

“I’m very pleased,” said Dr. Derek Angus, director of intensive care at the University of Pittsburgh Medical Center, who led one of the studies. Incredibly, all the other experiments were headed in the same direction. This is the most reliable information about how patients with COVID-19 are cared for.”

Mark Shannon, 61, a retired bank teller in Pittsburgh, was treated with the steroid hydrocortisone in the study and recovered. Shannon was on a ventilator for 11 days. His doctors told him that his recovery from such a long illness was remarkable.

“I realized how close I had come to losing my life,” he said.

The W.H.O. issued treatment recommendations on Wednesday, suggesting that steroids should be used in severely ill patients and not in milder ones.

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